The NPRL3 Antibody (N-Term) from MyBioSource.com is a Rabbit Polyclonal antibody to NPRL3. This antibody recognizes Human antigen. The NPRL3 Antibody (N-Term) has been validated for the following applications: Western Blot.
Description
As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling